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Language: English German. More than 30 years ago, John Wolfe was the first to observe and describe the association between breast density on mammography and increased breast cancer risk. Following this pioneer work, there is now compelling evidence that density in the highest quartile represents a 4—6 times higher risk of breast cancer.
The breast contains ducts, glands, fibrous connective tissue, and fatty tissue. Breasts that are dense or very dense have a lot of fibrous, connective tissue and less fatty tissue. Breasts that are not dense contain almost all fatty tissue and very little fibrous tissue. Virtually all women start out with very dense breast tissue.
Breasts contain glandular, connective, and fat tissue. Breast density is a term that describes the relative amount of these different types of breast tissue as seen on a mammogram. Dense breasts have relatively high amounts of glandular tissue and fibrous connective tissue and relatively low amounts of fatty breast tissue.
Breast cancer is the second leading cause of cancer death in women. Although mammography is well known to be a powerful screening tool in the detection of early breast cancer, it is imperfect, particularly for women with dense breasts. In women with dense breast tissue, the sensitivity of mammography is reduced.
Dense breast tissue is detected on a mammogram. Additional imaging tests are sometimes recommended for women with dense breasts. If a recent mammogram showed you have dense breast tissue, you may wonder what this means for your breast cancer risk.
Breast density is a strong, prevalent, and potentially modifiable risk factor for breast cancer, which makes it of special interest to clinicians whose jobs involve breast cancer risk prediction. Kerlikowske delivered the John I. Mammographic breast density is a radiologic term, Dr.
Patients with high breast density do benefit from a technology that enables surgeons to assess whether cancer cells remain on the margins of excised tissue during breast conserving surgery, known as a lumpectomyaccording to a UCI Health study. Lin, DO. Failure to achieve clear margins is a leading cause of reoperation in the treatment of early-stage breast canceras well as breast cancer recurrence. Dense breast tissue contains a higher percentage of glandular and fibrous tissue than fatty breasts, which makes it more difficult for tumors to be detected during a mammography.