By Charlotte Bath November 25, Advertisement. A joint efficacy analysis of the ABC Trials comparing a nonanthracycline regimen of the taxane docetaxel and cyclophosphamide TC vs standard chemotherapy with doxorubicin and cyclophosphamide AC plus a taxane TaxAC or TAC showed that invasive disease—free survival favored the anthracycline-containing regimens. The 4-year invasive disease—free survival rate was
Chemotherapy for breast cancer uses drugs to target and destroy breast cancer cells. These drugs are usually given directly into a vein through a needle or as a pill. Chemotherapy for breast cancer frequently is used in addition to other treatments, such as surgery, radiation or hormone therapy.
In fact, Taxol is the top-selling cancer drug worldwide. TC includes two drugs: a taxane, paclitaxel Taxol or docetaxel Taxotere ; and cyclophosphamide Cytoxan. So between them, you have some pretty powerful agents working to destroy your cancer.
Tell your doctor or nurse if you have any side effects so they can help you manage them. Your nurse will give you a contact number to ring if you have any questions or problems. If in doubt, call them. You might have one or more of them.
Clinical Trials: The NCCN recommends cancer patient participation in clinical trials as the gold standard for treatment. Cancer therapy selection, dosing, administration, and the management of related adverse events can be a complex process that should be handled by an experienced healthcare team. Clinicians must choose and verify treatment options based on the individual patient; drug dose modifications and supportive care interventions should be administered accordingly.
Chemotherapy drugs are a specific class of medications called cytotoxic agents. Cancer cells grow faster than regular cells. These drugs disrupt the growth of fast-growing cells and leave slower-growing cells generally unharmed.
Breast cancer is the second most common cancer in women worldwide. Although most women are diagnosed with early breast cancer, a substantial number recur due to persistent micro-metastatic disease. Systemic adjuvant chemotherapy improves outcomes and has advanced from first-generation regimens to modern dose-dense combinations.
After surgery to remove early-stage breast cancer, chemotherapy often is given to destroy any breast cancer cells that may remain in the body and reduce the risk of the cancer coming back recurrence. Doctors call chemotherapy given after surgery adjuvant chemotherapy. A number of chemotherapy medicines given alone or in combination are used as adjuvant chemotherapy, including a class of medicines called anthracyclines. The research was published online on April 11,
Study record managers: refer to the Data Element Definitions if submitting registration or results information. Both TAC docetaxel, doxorubicin, and cyclophosphamide and TC docetaxel and cyclophosphamide are established adjuvant chemotherapy regimens for early stage breast cancer. TAC, however, due to the inclusion of the anthracycline doxorubicin, carries a high risk of hematologic and cardiotoxic adverse effects.
If you're struggling to find what you need, call our Support line on 7 days a week, 8am-8pm. TC is a combination treatment used to treat breast cancer. It may also be used to treat other cancers. It is best to read this information with our general information about chemotherapy and the type of cancer you have.